REPORTS OF CITALOPRAM WITHDRAWAL REACTIONS
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DATE CITATION DRUG REPORT
| 1998 | Gram | Citalopram, paroxetine, fluvoxamine | Report, in Danish, gives brief details of reports of withdrawal reactions relating to citalopram (5 cases), paroxetine (5 cases) and fluvoxamine (1 case) |
| 2000 | Sempere et al | Citalopram | Letter re: withdrawal problems with citalopram (in Spanish) |
| 2000 | Fernando & Schwader | Citalopram | Case report in which a 45-year woman, taking 40mg/day citalopram experienced rapid-onset dizziness a few hours after missing her morning dose. On the second occasion this resulted in a minor car accident |
| 2001
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Nordeng et al | Paroxetine Fluoxetine Citalopram |
"Neonatal withdrawal syndrome commonly occurs in infants exposed during the third trimester to drugs known to cause addiction. We report five cases of neonatal withdrawal syndrome after third trimester in utero SSRI exposure. In three cases the mother used paroxetine in doses from 10mg to 40mg, one mother used citalopram 30mg, and one mother used fluoxetine 20mg. Withdrawal symptoms occurred within few days after birth and lasted up to one month after birth. Four of the infants needed treatment with chlorpromazine. Symptoms were irritability, constant crying, shivering, increased tonus, eating and sleeping difficulties and convulsions." |
The following are the recommendations and warnings relating to withdrawal
reactions for SSRI antidepressants in the Data Sheet Compendium 1999/2000:
Citalopram (CIPRAMIL): "Withdrawal reactions have been reported in association with
selective serotonin reuptake inhibitors (SSRIs), including cipramil. Common symptoms
include dizziness, paraesthesia, headache, anxiety and nausea. Abrupt discontinuation of
treatment with cipramil should be avoided. The majority of symptoms experienced on
withdrawal of SSRIs are non-serious and self-limiting."
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Contents page |
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References |
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Table: all reports of SSRI withdrawal |
