Department of Health
MEDICINES CONTROL AGENCY
Market Towers 1 Nine Elms Lane London SW8 5NQ
TEL:  020 7273 0400
FAX:  020 7273 0675	.Our Ref: OG/0234
	3 September 2002

Dear Mr Medawar,

Thank you for your letter of 2 August 2002.

The expert meeting that will consider issues relating to withdrawal reactions and dependence with SSRIs will be held on 21 November and we will bring the further data that you provide to the attention of the members.

You have asked for an explanation of differences between the CSM advice of March 1998 and the current Patient Information Leaflet for Seroxat and for copies of documents communicating the decisions of CSM and CPMP. We are currently getting this information for you and will respond to your requests by 14 September.

Yours sincerely

DR J M RAINE,

Director, Post-Licensing Division

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